

One of the main downsides to having the Gungeon Ant is its alternating fire, switching between fireballs and oil whenever you reload. Great Queen Ant (Gungeon Ant + Gilded Bullets, Coin Crown, Heck Blaster, Crown of Guns, or Ring of Fire Resistance)Īrguable the grossest synergy on this list, the Great Queen Ant gets 2nd place for how powerful this combo is in terms of damage. The limits are the imagination in this case.įor letting you feel like an anime character, even for a “brief” time, Knight Time gets 3rd place on this list.Ģ. If you need to escape from a hoard of Gunzookie, you can take the hit and escape. If you have an overpowered weapon, you can take a hit and then get in a shot with no resistance at all. While it’s usefulness is singular, it’s an amazing feeling to shoot up your enemies whenever you get hurt like you’re Quicksilver in Days of Future Past. With Knight Time, time briefly stops whenever you take damage. The only synergy on this list that isn’t a gun, it deserves Top 3 placement not just for its usefulness on a run, but for how fun it is to have. Knight Time (Ballistic Boots + Gunknight Greaves) It’s a practical synergy you can use against anything and everything, and that is why it makes the list.ģ. If you get Ice Water, you can knock back most enemies you come across with its considerable force, getting them out of the way so you can blast them with your other absurd combinations. Ice Water causes the Mega Douser’s water to freeze enemies, making them move slower, and increases the size of the gun’s water stream. While both guns deal an additional 30% damage when paired together, it’s what happens to the Mega Douser that makes this combo worth pursuing.
#ENTER THE GUNGEON SYNERGIES UPGRADE#
Ice Water is a powerful upgrade to the Mega Douser, a water gun that you can get fairly easy alongside another gun that shows up often. If you’re ever wanted to shoot ice water at your enemies until they cease to be, I’ve got a synergy for you.

If you’re able to pick up ammo reloads along your way all you will need is this gun to pass through 95% of enemies. On the other hand, the VertebraeK-47 is able to freeze enemies with this combo. The Jolly Roger links together skull-bullets that the Skull Splitter fires, turning shots into a 3-skull chain that you can use to spam enemies to hell. What makes this synergy so powerful is specifically how the VertebraeK-47 affects the Skull Splitter. The two bone-themed guns are powerful on their own and even more-so together. The combo that got me to the High Dragun with minimal experience, the Jolly Roger is an overpowered delight and one you can get early on. Jolly Roger (Skull Splitter + VertebraeK-47) Of the gungeon's synergies, there are some that have meager effects, while others are an incredible help. Synergies occur when two items work to better each other, whether it be increasing gun damage or item potency. In a game as notoriously difficult as Enter the Gungeon, you need whatever edge you can get one of the best being synergies.
